Efficacy of Femtosecond Laser-Assisted Phacoemulsification for Cataract Patients and its Influence on Serum Levels of Inflammatory Factors.

OBJECTIVE: To investigate effect of femtosecond laser-assisted phacoemulsification in treating cataract patients, and to analyse its influence on serum inflammatory factors IL-6, IL-1β, TNF-α .

STUDY DESIGN: An analytical, descriptive study.

PLACE AND DURATION OF STUDY: The Ophthalmologic Center, Rehabilitation Center Hospital of Gansu, China, from January 2016 to September 2017.

METHODOLOGY: A total of 94 eyes were randomly divided into control group (47 cases) and observation group (47 cases). Control group was treated with traditional phacoemulsification. The observation group was added with femtosecond laser based on the treatment of the control group. Clinical efficacy of two groups was compared.

RESULTS: Surgery time of the observation group was longer than that of the control group (p<0.001). Effective phacoemulsification time, cumulative dissipated energy, and liquid flow of the observation group were all less than those of the control group (all p<0.001). One day after surgery, aqueous flare and rate of corneal endothelium loss in the observation group were less than those of the control group (both p<0.001). Seven days after surgery, serum levels of IL-6, IL-1 and TNF- in the observation group were lower than those of the control group (all p<0.001).

CONCLUSION: Femtosecond laser-assisted phacoemulsification has better clinical effect in treating cataract, and can reduce the energy and time cost in the phacoemulsification, decrease the serum levels of inflammatory factors and cause less postoperative complications. But it takes longer operation time and relatively higher treatment cost.