Add like
Add dislike
Add to saved papers

Next-Generation Ecological Immunology.

The application of next-generation sequencing (NGS) to the study of whole genomes and transcriptomes is becoming commonplace in molecular biology and molecular medicine. Over the past decade, these technologies have become more accessible to the broader biological community as the cost of NGS has decreased significantly and the availability of ready-to-use library preparation kits and user-friendly bioinformatic tools has increased. Indeed, these technologies are starting to be deployed in the study of ecological systems and immune function and have already yielded new discoveries and insights. However, despite the power of these techniques, they remain underutilized by the ecological immunology (ecoimmunology) community. This is unfortunate because there are several key challenges faced by ecological immunologists that these technologies are particularly well suited to address: (1) to measure immune function in biologically meaningful ways, (2) to describe the complex relationship between immunology and other aspects of physiology in an ecological context, and (3) to relate ecoimmunology to disease ecology. Each of these three challenges confronting the ecoimmunology community is critical to understanding ecoimmunology, and each has been stymied by a lack of sufficient data to effectively tackle the questions at hand. Deploying NGS methods to tackle these challenges promises to revolutionize the field of ecoimmunology by facilitating the unbiased, broad-scale, and efficient discovery of novel immune genes and mechanisms; the quantification of variation in immune systems; the characterization of relevant physiological pathways; and the description of microbial communities.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app