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Is Fasting Necessary for Individuals With Nonalcoholic Fatty Liver Disease to Undergo Vibration-Controlled Transient Elastography?
American Journal of Gastroenterology 2019 January 24
OBJECTIVES: To investigate the effect of meal intake on liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) in patients with biopsy-proven nonalcoholic fatty liver disease undergoing vibration-controlled transient elastography.
METHODS: LSM and CAP were assessed at baseline and serially for 6 hours after meal intake in 24 patients.
RESULTS: A significant increase in LSM was seen up to the 2-hour time point (26 ± 25%, P = 0.02). The CAP scores changed minimally with a maximal change of 3% (P > 0.1).
CONCLUSIONS: Three hours of fasting is necessary before evaluation with vibration-controlled transient elastography.
METHODS: LSM and CAP were assessed at baseline and serially for 6 hours after meal intake in 24 patients.
RESULTS: A significant increase in LSM was seen up to the 2-hour time point (26 ± 25%, P = 0.02). The CAP scores changed minimally with a maximal change of 3% (P > 0.1).
CONCLUSIONS: Three hours of fasting is necessary before evaluation with vibration-controlled transient elastography.
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