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CAPAM: The mRNA Cap Adenosine N6-Methyltransferase.
Trends in Biochemical Sciences 2019 January 22
The mRNA cap is a structure that protects mRNA from degradation and recruits processing and translation factors. A new mRNA capping enzyme has been identified, PCIF1/CAPAM, which methylates adenosine when it is the first transcribed nucleotide. This discovery is crucial for understanding the function of cap adenosine methylation.
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