We have located links that may give you full text access.
The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature.
Journal of Aging and Physical Activity 2019 January 25
BACKGROUND:: Variations in genotype may contribute to heterogeneity in functional adaptations to exercise.
METHODS:: A systematic search of 8 databases was conducted, and 9696 citations were screened.
RESULTS:: Eight citations from 7 studies measuring 10 single nucleotide polymorphisms (SNPs) and 9 different functional performance test outcomes were included in the review. There was one observational study of physical activity and 6 experimental studies of aerobic or resistance training. The ACE (D) allele, ACTN3 (RR) genotype, UCP2 (GG) genotype, IL6-174 (GG), TNFα-308 (GG) and IL10-1082 (GG) genotype all predicted significantly superior adaptations in at least one functional outcome in older men and women after prescribed exercise or in those with higher levels of physical activity.
CONCLUSION:: There is a small amount of evidence that older adults may have better functional outcomes after exercise/physical activity if they have specific alleles related to musculoskeletal function or inflammation. However, more robust trials are needed.
METHODS:: A systematic search of 8 databases was conducted, and 9696 citations were screened.
RESULTS:: Eight citations from 7 studies measuring 10 single nucleotide polymorphisms (SNPs) and 9 different functional performance test outcomes were included in the review. There was one observational study of physical activity and 6 experimental studies of aerobic or resistance training. The ACE (D) allele, ACTN3 (RR) genotype, UCP2 (GG) genotype, IL6-174 (GG), TNFα-308 (GG) and IL10-1082 (GG) genotype all predicted significantly superior adaptations in at least one functional outcome in older men and women after prescribed exercise or in those with higher levels of physical activity.
CONCLUSION:: There is a small amount of evidence that older adults may have better functional outcomes after exercise/physical activity if they have specific alleles related to musculoskeletal function or inflammation. However, more robust trials are needed.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app