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Genomics of Prostate Cancer: What Nurses Need to Know

Katharine M McReynolds, Laurie M Connors
Seminars in Oncology Nursing 2019 January 18

OBJECTIVE: To review the current state of genomics and genetic testing in prostate cancer.

DATA SOURCES: National guidelines, evidence-based summaries, peer-reviewed studies, and Web sites. A case study is presented to illustrate key points.

CONCLUSION: Genetic profiling of prostate cancer tumors (somatic) and genetic testing of men with aggressive or metastatic disease (germline) are available.

IMPLICATIONS FOR NURSING PRACTICE: Nurses have a role in personalized health care and should be familiar with genetic testing options in prostate cancer because results may have implications for treatment options and at-risk family members. Hereditary cancer genetics can be complex and referrals to genetics specialists should be considered for hereditary cancer risk assessment and possible genetic testing.


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