We have located links that may give you full text access.
Perceived Versus Actual Aeroallergen Sensitization in Urban Children.
Journal of Allergy and Clinical Immunology in Practice 2019 January 15
BACKGROUND: Individuals often report allergy to specific aeroallergens, but allergy testing can reveal disparate sensitization.
OBJECTIVE: To characterize the agreement between perceived and actual sensitization to individual aeroallergens in an urban pediatric population.
METHODS: 253 children were enrolled from pediatric clinics in New York, NY. Detailed questionnaires regarding perceived sensitization and serum specific IgE measurements to ten common aeroallergens were completed. Agreement between perceived and actual sensitization (sIgE ≥ 0.35 kUA /L) to individual aeroallergens was assessed by Cohen's Kappa. Multivariable logistic regression models adjusted for potential confounders were used to test for associations between perceived and actual sensitization.
RESULTS: 161 (63.6%) of the 253 children reported perceived sensitization to ≥1 aeroallergen, and 203 (80.2%) were actually sensitized to ≥1 aeroallergen. Agreement between perceived and actual aeroallergen sensitization was fair for most aeroallergens, with greatest agreement for cat dander (Kappa 0.42, 95% CI 0.32-0.53) and dust (Kappa 0.32, 95% CI 0.20-0.44). Models adjusted for potential confounders showed nearly 6-fold odds of sensitization to cat dander given perceived cat allergy (aOR 5.82, 95%CI 2.91-11.64), and over 2-fold odds of sensitization to D. pteronyssinus, D. farinae, dog dander, or grass pollen given perceived sensitization to their respective allergens. Among children with no perceived sensitization, actual sensitization ranged from 5.4% to 30.4%, and was more common for indoor vs. outdoor allergens, including cockroach.
CONCLUSION: Children who perceive allergen sensitization to cat, dog, dust or grass are likely to demonstrate actual sensitization to these individual allergens. Children with no perceived sensitization to allergens are nonetheless frequently sensitized.
OBJECTIVE: To characterize the agreement between perceived and actual sensitization to individual aeroallergens in an urban pediatric population.
METHODS: 253 children were enrolled from pediatric clinics in New York, NY. Detailed questionnaires regarding perceived sensitization and serum specific IgE measurements to ten common aeroallergens were completed. Agreement between perceived and actual sensitization (sIgE ≥ 0.35 kUA /L) to individual aeroallergens was assessed by Cohen's Kappa. Multivariable logistic regression models adjusted for potential confounders were used to test for associations between perceived and actual sensitization.
RESULTS: 161 (63.6%) of the 253 children reported perceived sensitization to ≥1 aeroallergen, and 203 (80.2%) were actually sensitized to ≥1 aeroallergen. Agreement between perceived and actual aeroallergen sensitization was fair for most aeroallergens, with greatest agreement for cat dander (Kappa 0.42, 95% CI 0.32-0.53) and dust (Kappa 0.32, 95% CI 0.20-0.44). Models adjusted for potential confounders showed nearly 6-fold odds of sensitization to cat dander given perceived cat allergy (aOR 5.82, 95%CI 2.91-11.64), and over 2-fold odds of sensitization to D. pteronyssinus, D. farinae, dog dander, or grass pollen given perceived sensitization to their respective allergens. Among children with no perceived sensitization, actual sensitization ranged from 5.4% to 30.4%, and was more common for indoor vs. outdoor allergens, including cockroach.
CONCLUSION: Children who perceive allergen sensitization to cat, dog, dust or grass are likely to demonstrate actual sensitization to these individual allergens. Children with no perceived sensitization to allergens are nonetheless frequently sensitized.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app