We have located links that may give you full text access.
In vitro activity of colistin in combination with various antimicrobials against Acinetobacter baumannii species, a report from South Iran.
Introduction: Acinetobacter baumannii is a gram-negative,opportunistic pathogen responsible for resistant nosocomial infections especially in the intensive care units (ICUS).One reason for the failure in the treatment of A. baumannii is its ability of develop resistance against several antimicrobials. combination of different antimicrobials can be used to overcome such a resistance. This study was done to evaluate the in vitro synergistic activity of colistin in combination with six different antimicrobials, including ciprofloxacin, levofloxacin, imipenem, meropenem, ampicillin-sulbactam, and rifampin against A. baumannii species isolated from blood culture of patients admitted to ICUs of Nemazee hospital, Shiraz, Iran.
Method: After performing biochemical identification assays on 20 isolates of A. baumannii , minimum inhibitory concentrations were determined by E- test method and antibiotic interactions were assessed using broth microdilution checkerboard method.
Results: Combinations of colistin with all six studied antimicrobials had some synergistic effect.
Conclusion: clinical studies are required to clarify the therapeutic potential of these antimicrobial combinations.
Method: After performing biochemical identification assays on 20 isolates of A. baumannii , minimum inhibitory concentrations were determined by E- test method and antibiotic interactions were assessed using broth microdilution checkerboard method.
Results: Combinations of colistin with all six studied antimicrobials had some synergistic effect.
Conclusion: clinical studies are required to clarify the therapeutic potential of these antimicrobial combinations.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app