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Plant ISOform sequencing database (PISO): a comprehensive repertory of full-length transcripts in plants.
Plant Biotechnology Journal 2019 January 12
In higher eukaryotes, alternative splicing (AS) and alternative polyadenylation (APA) events can produce multiple transcript isoforms in the majority of genes, which significantly increase the protein-coding potential of a genome (Pan et al., 2008; Anvar et al., 2018). Different transcript isoforms might encode proteins with different functions or affect the mRNA stability and translational capacity, in some sense AS and APA events can dramatically increase the complexity and flexibility of the entire transcriptome and proteome (Yang et al., 2016; Feng et al., 2015; Li et al., 2017a; Wang et al., 2017a). Many databases contained AS events and transcripts in animals are available in some public resources such as ASTD and MAASE (Zheng et al., 2005), whereas there is no database containing full-length transcripts and AS events in plants up to now. This article is protected by copyright. All rights reserved.
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