[Analysis of the effectiveness of Dexmedetomidine in the treatment of degenerative diseases of the lumbar spine with minimally invasive puncture techniques in elderly patients.]

The aim of the study was a comparative analysis of the effectiveness of the use of Dexmedetomidine and Propofol in the treatment of degenerative diseases of the lumbar spine with minimally invasive puncture techniques in elderly patients. The study included 83 elderly patients (over 60 years old) who underwent laser denervation of facet joints (n=44) and posterolateral transforaminal endoscopic discectomy (n=39): in the first group, Dexmedetomidine (n=32), in the second group - Propofol (n=51). For the comparative analysis, gender characteristics (gender, age), constitutional features (height, weight, body mass index), the degree of physical status by ASA, the intensity of the pain syndrome before surgery, the duration of the operation, the degree of patient satisfaction with the Macnab surgery, the complications. In the dynamics analyzed: the level of sedation on the scales RASS and Ramsay; intraoperative parameters of cardiovascular and respiratory systems (systolic blood pressure, heart rate, hemoglobin oxygen saturation (SpO2), level of pain syndrome according to VAS in the field of operative intervention. As a result, it has been established that the use of Dexmedetomidine in minimally invasive puncture techniques in elderly patients allows ensure safety and efficacy in the perioperative period, a sufficient degree of sedation and analgesia without depression of the cardio-respiratory system.