Treatment of erlotinib induced acneiform eruption with chromophore gel-assisted phototherapy.

A 49-year-old female presented with an acneiform eruption induced by erlotinib. She had been diagnosed with Stage IV (T1N3M1) EGFR mutant adenocarcinoma of the lung and commenced on erlotinib 150mg daily. Within three days she developed an acneiform eruption prompting empiric treatment with topical hydrocortisone and systemic doxycycline 100mg daily. The acneiform eruption progressed with evolution to widespread pustules and papules with proud erythema involving the entire face with minor extension to the scalp, décolletage and back (Fig. 1). This article is protected by copyright. All rights reserved.