We have located links that may give you full text access.
Cognitive training benefit depends on brain injury location in adolescents with traumatic brain injury: a pilot study.
European Journal of Physical and Rehabilitation Medicine 2018 December 15
BACKGROUND: Executive dysfunctioning after pediatric traumatic brain injury (TBI) has been linked to poor outcomes in school performance, social functioning and employment. The credibility of training-induced cognitive enhancement in TBI is threatened by its limited proof of benefit in executive skills of daily living.
AIM: Our primary aim was to investigate if cognitive intervention for improving impairments in executive functions in the chronic stage of traumatic brain injury is effective during adolescence. The secondary aim was to explore whether training benefit is driven by injury location.
DESIGN: Prospective observational study.
SETTING: Child Rehabilitation Center, Ghent University Hospital, Belgium.
POPULATION: Sixteen adolescents with moderate to severe TBI (mean age 15y8m) and sixteen age and gender matched healthy peers were included.
METHODS: Effects of a new cognitive training program (BrainGames) were assessed post-intervention and 6 months later utilizing a comprehensive neuropsychological test-battery and the Behavior Rating Inventory of Executive Function. In addition, subgroup analyses were performed to determine long-term training benefit in the presence of lesions in corpus callosum, deep-brainnuclei and prefrontal cortex.
RESULTS: Adolescents with TBI showed significant improvements on measures of executive functioning at completion of the training and at follow-up compared with the pre-tests. The presence or absence of diffuse-axonal-injuries (DAI) in the deep brain nuclei determined a significant difference in long-term training benefit.
CONCLUSIONS: This study provides preliminary evidence that cognitive training, beyond the acute rehabilitation period in adolescents with TBI is effective to boost executive functioning in daily living. Furthermore we indicated that DAI in deep brain nuclei may jeopardize long-term benefit from cognitive training.
CLINICAL REHABILITATION IMPACT: Individualized rehabilitation programs are crucial in adolescents with different locations of TBI-lesions. Long term follow up of pediatric traumatic brain injury is essential.
AIM: Our primary aim was to investigate if cognitive intervention for improving impairments in executive functions in the chronic stage of traumatic brain injury is effective during adolescence. The secondary aim was to explore whether training benefit is driven by injury location.
DESIGN: Prospective observational study.
SETTING: Child Rehabilitation Center, Ghent University Hospital, Belgium.
POPULATION: Sixteen adolescents with moderate to severe TBI (mean age 15y8m) and sixteen age and gender matched healthy peers were included.
METHODS: Effects of a new cognitive training program (BrainGames) were assessed post-intervention and 6 months later utilizing a comprehensive neuropsychological test-battery and the Behavior Rating Inventory of Executive Function. In addition, subgroup analyses were performed to determine long-term training benefit in the presence of lesions in corpus callosum, deep-brainnuclei and prefrontal cortex.
RESULTS: Adolescents with TBI showed significant improvements on measures of executive functioning at completion of the training and at follow-up compared with the pre-tests. The presence or absence of diffuse-axonal-injuries (DAI) in the deep brain nuclei determined a significant difference in long-term training benefit.
CONCLUSIONS: This study provides preliminary evidence that cognitive training, beyond the acute rehabilitation period in adolescents with TBI is effective to boost executive functioning in daily living. Furthermore we indicated that DAI in deep brain nuclei may jeopardize long-term benefit from cognitive training.
CLINICAL REHABILITATION IMPACT: Individualized rehabilitation programs are crucial in adolescents with different locations of TBI-lesions. Long term follow up of pediatric traumatic brain injury is essential.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app