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Effect of Menstrugole on primary dysmenorrhea: a randomized clinical trial.

Objective: Primary dysmenorrhea occurs in more than 50% of women of reproductive age. This survey evaluated the effects of Menstrugole on the alleviation of primary dysmenorrhea.

Methods: This study was performed in western Iran between August 15 and December 15, 2017, in female students with primary dysmenorrhea. The students were randomly divided into 2 groups and received placebo or a Menstrugole capsule for 3 days in each of 2 menstrual cycles. The visual analog scale was used to assess pain severity. The χ2 test, one-way analysis of variance, and the paired t -test were used for statistical evaluation.

Results: We compared the severity of pain between the 2 groups. There was a significant change in the mean pain score during the first ( P <0.001) and second months ( P <0.001) after the use of Menstrugole, compared with that in the placebo group.

Conclusion: Menstrugole decreased pain severity in female students, and can be considered by health care providers for treatment of primary dysmenorrhea.

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