["Decoratively figured blisters" on the whole integument in initially diagnosed ulcerative colitis]

Wolfgang Konschake, Georg Daeschlein, Michael Jünger, Stine Lutze
Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete 2018 November 20
The rare case of a 61-year-old patient suffering from linear IgA dermatosis is presented. The patient was previously hospitalized with chronic inflammatory bowel disease. The correct diagnosis of the disease was based on clinical and histological findings. Serological methods, such as indirect immunofluorescence, ELISA and immunoblotting are suitable for identification of the autoantibodies. In this case the detection of IgA antibodies along the basal membrane was achieved by direct immunofluorescence. Other bullous dermatoses with similar symptoms, such as an IgG-mediated bullous pemphigoid have to be excluded. The therapy of linear IgA dermatosis is ensured by steroid-containing topical agents, alongside antiseptic measures as well as systemic dapsone p.o.

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