Cancer Biology Aspects of Computational Methods & Applications in Drug Discovery.

BACKGROUND: Cancer is one of the most debilitating diseases in the world. Even though advances in molecular and cellular biology have contributed to the decline of mortality associated with cancer, the procedure of drug discovery and development of cancer is time-consuming and expensive. However, with computer-aided drug discovery (CADD) techniques, pharmaceutical firms can save production costs and reduce the time of introducing effective anticancer drugs to the market. CADD strategies like structure-based, ligand-based, and combined structure-based and ligand-based approaches also have the advantage of identifying target sites and discovering active compounds with high affinity for the target sites. In this article has been reviewed research carried out on cancer biology aspect of the computational methods in drug discovery.

OBJECTIVE: The main objective of the study is to identity one of the most dangerous disease named cancer' causes and its development in human body. In addition to this, its recovery has also been discussed briefly.

CONCLUSIONS: Our findings indicate that only a few studies have been carried out regarding this area of research. Hence, it is recommended that further research should be conducted on the computational methods for identifying candidate drugs cancers for colon cancer, prostate cancer, and other types of cancer.