[The analysis of serum allergen spectrum in 0－12 years old children with allergic diseases in Liaoning Province].

Objective: To explore the distribution and characteristics of allergens in children aged 0－12 years old in liaoning province. Method: 46 620 children with suspected allergic diseases were grouped according to age, sex and detection time. Then allergen detections were conducted. The distribution of allergen in different groups was analyzed. Result: Most children were sensitized to single allergen, followed by a double positive. 98.08% children showed sensitivities to up to five kinds of allergen. The allergen spectrum of patients in different age groups was slightly different. With the increase of age, the rate, degree and number of allergen positive are generally on the rise. The positive rate and degree of each allergen were statistically significant in different age groups, seasons and genders, but not the trend and degree of variation. The onset time in this region is relatively concentrated in July to September, and the incidence of allergen in summer and autumn is higher than that in winter and spring. Conclusion: In Liaoning Province, household dust mites, animal dander, egg white, milk are the main allergens in patients with allergic disease, and the onset time is relatively concentrated in summer and autumn. Clear the main allergens, the region characteristic and changing trend is conducive to the treatment of allergic disease take effective and preventive measures.