We have located links that may give you full text access.
Nitrosative stress indices in dogs with neurological form of canine distemper.
This is a prospective, controlled, randomized clinical study to evidence the role of nitrosative stress in development of overt neurological sign of canine distemper (CD). The enrollment of cases wasa made on basis of overt sign of CD (n=139) and the findings were compared with apparently healthy dogs (n=15). The CD specific immunoglobulins resulted in 94 confirmed positive cases. The nitric oxide (NO) and neuronal nitric oxide synthase (nNOS) concentration in cerebrospinal fluid (CSF) (18.08 ± 2.76, 415.84 ± 46.24, respectively) and plasma (32.68 ± 4.31, 321.31 ± 102.30, respectively) were significantly (P<0.05) elevated as compared to healthy control group. The concentration of neuron specific enolase (NSE) in CSF and plasma were also significantly (P<0.05) higher in dogs suffering from CD. The significant differences in other biochemical parameters like total protein, albumin and globulin were found in the CSF of dogs compared with healthy control. The author concludes that NO plays a role in pathophysiology of neurological form of CD and nNOS and NSE estimation in CSF and plasma could help in making early diagnosis of clinical cases.
Full text links
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app