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The Study of Nrf2 Signaling Pathway in Ovarian Cancer

Xiaotong Wu, Li Ying Han, Xiao Xiao Zhang, Ling Wang
Critical Reviews in Eukaryotic Gene Expression 2018, 28 (4): 329-336
Ovarian cancer is one of the most malignant gynecological tumors in the world, with a high fatality rate and resistance to chemotherapy. Much basic research has revealed that oxidative stress is involved in tumor occurrence and development processes and is associated with tumor progression as well as metastasis. In recent years, oxidative stress has been proven to have a close connection with malignant biological behavior in ovarian cancer, and this topic has garnered increasing attention. This article reviews the research aimed toward elucidating the relationship between oxidative stress and ovarian cancer.


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