We have located links that may give you full text access.
The Effectiveness of Intermittent Pneumatic Compression in Therapy of Lymphedema of Lower Limbs: Methods of Evaluation and Results.
Lymphatic Research and Biology 2019 Februrary
BACKGROUND: Evaluation of intermittent pneumatic compression (IPC) in lymphedema is classically based on measurements of circumferences and volume of the edematous limb. However, although important, it provides only a general information without insight into what proceeds under the skin with respect to hydromechanical and structural changes.
AIM AND METHODS: We present the multimodal evaluation of the effectiveness of IPC device in limb edema by measuring tissue stiffness, fluid pressure, and flow volume, and lymphoscintigraphic and near-infrared fluorescence (NIRF) indocyanine green (ICG) lymphography imaging of edema fluid movement, before and after one 45-60 minute compression cycle in over 50 patients with lymphedema stage II and III.
RESULTS: (1) Tissue fluid pressures were lower than those applied by IPC device. (2) The higher the applied compression force, the larger the flow volume. (3) Skin stiffness (superficial tonometry) decreased mainly in the calf, whereas, subcutaneous tissue (deep tonometry) was observed at all limb levels. (4) Skin water concentration (dielectric constant) was only insignificantly decreased, but subcutaneous extracellular water (bioimpedance Ldex index, fluid movement force test) was effectively moved away to limb proximal regions. (5) Imaging tissue (edema) fluid flow pathways on lymphoscintigram and real-time flow on NIRF ICG video could be observed and were evaluated semiquantitatively.
CONCLUSIONS: Adjustment of compression parameters to tissue stiffness, fluid accumulation volumes, and fluid movement ability (hydraulic conductivity of tissues) at various limb levels is indispensable for effective therapy. Redesigning of compression devices will be needed to enable applying differentiated compression pressures and prolonged timings at various limb levels.
AIM AND METHODS: We present the multimodal evaluation of the effectiveness of IPC device in limb edema by measuring tissue stiffness, fluid pressure, and flow volume, and lymphoscintigraphic and near-infrared fluorescence (NIRF) indocyanine green (ICG) lymphography imaging of edema fluid movement, before and after one 45-60 minute compression cycle in over 50 patients with lymphedema stage II and III.
RESULTS: (1) Tissue fluid pressures were lower than those applied by IPC device. (2) The higher the applied compression force, the larger the flow volume. (3) Skin stiffness (superficial tonometry) decreased mainly in the calf, whereas, subcutaneous tissue (deep tonometry) was observed at all limb levels. (4) Skin water concentration (dielectric constant) was only insignificantly decreased, but subcutaneous extracellular water (bioimpedance Ldex index, fluid movement force test) was effectively moved away to limb proximal regions. (5) Imaging tissue (edema) fluid flow pathways on lymphoscintigram and real-time flow on NIRF ICG video could be observed and were evaluated semiquantitatively.
CONCLUSIONS: Adjustment of compression parameters to tissue stiffness, fluid accumulation volumes, and fluid movement ability (hydraulic conductivity of tissues) at various limb levels is indispensable for effective therapy. Redesigning of compression devices will be needed to enable applying differentiated compression pressures and prolonged timings at various limb levels.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app