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JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Physicochemical properties and in vivo evaluation of Pt/TiO 2 -SiO 2 nanopowders.
Nanomedicine 2018 September
AIM: Sol-gel is a suitable and advantageous method to synthesize mixed oxide nanomaterials with unique physicochemical and biological properties.
MATERIALS & METHODS: In this work, TiO2 -SiO2 nanopowders cogeled with platinum acetylacetonate were developed and studied in the perspective of nanomedicine. The physicochemical properties of the Pt/TiO2 -SiO2 nanopowders, named NanoRa2 -Pt, were evaluated in detail by means of complementary spectroscopic and microscopic tools. The nanopowder's biocatalytic efficiency in wound healing was evaluated in a Type I diabetes animal model.
RESULTS: These are TiO2 -SiO2 submicron mesoporous particles with variable size and shape containing ultra-small platinum nanoparticles with catalytic properties.
CONCLUSION: The use of NanoRa2 -Pt catalyzes the natural healing processes with a faster remodeling stage. These sols, which we call nanobiocatalysts, belong to an emerging and very promising research field known as catalytic nanomedicine.
MATERIALS & METHODS: In this work, TiO2 -SiO2 nanopowders cogeled with platinum acetylacetonate were developed and studied in the perspective of nanomedicine. The physicochemical properties of the Pt/TiO2 -SiO2 nanopowders, named NanoRa2 -Pt, were evaluated in detail by means of complementary spectroscopic and microscopic tools. The nanopowder's biocatalytic efficiency in wound healing was evaluated in a Type I diabetes animal model.
RESULTS: These are TiO2 -SiO2 submicron mesoporous particles with variable size and shape containing ultra-small platinum nanoparticles with catalytic properties.
CONCLUSION: The use of NanoRa2 -Pt catalyzes the natural healing processes with a faster remodeling stage. These sols, which we call nanobiocatalysts, belong to an emerging and very promising research field known as catalytic nanomedicine.
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