Topography-Guided Custom Photorefractive Keratectomy for Myopia in Primary Eyes With the WaveLight EX500 Platform.

PURPOSE: To evaluate the outcomes after topography-guided ablation treatment (T-CAT) for the correction of myopia and myopic astigmatism with photorefractive keratectomy (PRK).

METHODS: This was a retrospective, non-comparative case series study of 25 patients (40 eyes) with low to moderate myopia with or without astigmatism who underwent topography-guided custom PRK with the Wave-Light EX500 excimer laser platform (Alcon Laboratories, Inc., Fort Worth, TX). The customized treatment plan was based on Topolyzer Vario topography system (Alcon Laboratories, Inc.) data. The patients were observed for 6 months after the procedure.

RESULTS: The surgery significantly reduced the manifest refractive spherical equivalent (MRSE), sphere, and cylinder (P < .05) at 6 months of follow-up. Compared with the preoperative corrected distance visual acuity (CDVA), 8 (20%) and 10 (25%) of 40 eyes gained one or more lines of postoperative uncorrected distance visual acuity at 3 and 6 months, respectively. Only 1 eye presented loss of one line of CDVA at 6 months postoperatively, which was due to delayed epithelial healing. Ten patients (15 eyes) reported symptoms related to dry eye and the vision of 21 patients (17 eyes) fluctuated during the first month.

CONCLUSIONS: The T-CAT custom PRK procedure provided good early outcomes for treating patients with low to moderate myopia with or without astigmatism. [J Refract Surg. 2018;34(8):541-546.].