One-Step Hydrothermal Approach to Synthesis Carbon Dots from D-Sorbitol for Detection of Iron(III) and Cell Imaging

Junqiu Zhang, Juping Yan, Yingte Wang, Yong Zhang
Journal of Nanoscience and Nanotechnology 2018 July 1, 18 (7): 4457-4463
A facile and economic approach to synthesis highly fluorescence carbon dots (CDs) via one-step hydrothermal treatment of D-sorbitol was presented. The as-synthesized CDs were characterized by good water solubility, well monodispersion, and excellent biocompatibility. Spherical CDs had a particle size about 5 nm and exhibited a quantum yield of 8.85% at excitation wavelength of 360 nm. In addition, the CDs can serve as fluorescent probe for sensitive and selective detection of Fe3+ ions with the detection limit of 1.16 μM. Moreover, the potential of the as-prepared carbon dots for biological application was confirmed by employing it for fluorescence imaging in MCF-7 cells.

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