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Raising concerns about the Sepsis-3 definitions.

Massimo Sartelli, Yoram Kluger, Luca Ansaloni, Timothy C Hardcastle, Jordi Rello, Richard R Watkins, Matteo Bassetti, Eleni Giamarellou, Federico Coccolini, Fikri M Abu-Zidan, Abdulrashid K Adesunkanmi, Goran Augustin, Gian L Baiocchi, Miklosh Bala, Oussema Baraket, Marcelo A Beltran, Asri Che Jusoh, Zaza Demetrashvili, Belinda De Simone, Hamilton P de Souza, Yunfeng Cui, R Justin Davies, Sameer Dhingra, Jose J Diaz, Salomone Di Saverio, Agron Dogjani, Mutasim M Elmangory, Mushira A Enani, Paula Ferrada, Gustavo P Fraga, Sabrina Frattima, Wagih Ghnnam, Carlos A Gomes, Souha S Kanj, Aleksandar Karamarkovic, Jakub Kenig, Faryal Khamis, Vladimir Khokha, Kaoru Koike, Kenneth Y Y Kok, Arda Isik, Francesco M Labricciosa, Rifat Latifi, Jae G Lee, Andrey Litvin, Gustavo M Machain, Ramiro Manzano-Nunez, Piotr Major, Sanjay Marwah, Michael McFarlane, Ziad A Memish, Cristian Mesina, Ernest E Moore, Frederick A Moore, Noel Naidoo, Ionut Negoi, Richard Ofori-Asenso, Iyiade Olaoye, Carlos A Ordoñez, Mouaqit Ouadii, Ciro Paolillo, Edoardo Picetti, Tadeja Pintar, Alfredo Ponce-de-Leon, Guntars Pupelis, Tarcisio Reis, Boris Sakakushev, Hossein Samadi Kafil, Norio Sato, Jay N Shah, Boonying Siribumrungwong, Peep Talving, Cristian Tranà, Jan Ulrych, Kuo-Ching Yuan, Fausto Catena
World Journal of Emergency Surgery : WJES 2018
The Global Alliance for Infections in Surgery appreciates the great effort of the task force who derived and validated the Sepsis-3 definitions and considers the new definitions an important step forward in the evolution of our understanding of sepsis. Nevertheless, more than a year after their publication, we have a few concerns regarding the use of the Sepsis-3 definitions.

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