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Genetic analysis of TMEM230 in Japanese patients with familial Parkinson's disease.
Parkinsonism & related Disorders 2018 March
We investigated the prevalence of TMEM230, a novel pathogenic mutation in autosomal dominant Parkinson's disease (PD) by screening 182 Japanese patients, in which no coding mutations were detected. Reviewing with previous studies, our findings suggest that TMEM230 mutations may not play a role in the development of familial PD.
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