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Double-blind study of botulinum toxin in spasmodic torticollis.

J K Tsui, A Eisen, A J Stoessl, S Calne, D B Calne
Lancet 1986 August 3
In a double-blind trial in 21 patients with spasmodic torticollis botulinum-A toxin produced both subjective and objective improvement, including significant pain relief in 14 of the 16 patients presenting with pain. Side-effects were more frequently reported during placebo administration and no significant systemic adverse reactions were noted.

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