Premenstrual disorders

Kimberly Ann Yonkers, Michael K Simoni
American Journal of Obstetrics and Gynecology 2018, 218 (1): 68-74
Premenstrual disorders include premenstrual syndrome, premenstrual dysphoric disorder, and premenstrual worsening of another medical condition. While the underlying causes of these conditions continue to be explored, an aberrant response to hormonal fluctuations that occurs with the natural menstrual cycle and serotonin deficits have both been implicated. A careful medical history and daily symptom monitoring across 2 menstrual cycles is important in establishing a diagnosis. Many treatments have been evaluated for the management of premenstrual disorders. The most efficacious treatments for premenstrual syndrome and premenstrual dysphoric disorder include serotonin reuptake inhibitors and contraceptives with shortened to no hormone-free interval. Women who do not respond to these and other interventions may benefit from gonadotropin-releasing hormone agonist treatment.


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If you are suffering from mood disorder or worsening of your medical conditions prior to your menstrual cycles , you may benefit from some hormonal birth control pills or need to take specific antidepressants to help relieve your symptoms.
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