JOURNAL ARTICLE

Lipofibromatous hamartoma of the median nerve: 3T MRI evaluation by constrained spherical deconvolution analysis

Alessandro Arrigo, Michele Gaeta, Alessandro Calamuneri, Enricomaria Mormina, Silvia Marino, Francesco Stagno d'Alcontres, Marcello Longo, Francesca Granata
Neuroradiology Journal 2018, 31 (4): 445-448
28541095
In this study we described a case of lipofibromatous hamartoma involving the median nerve. We adopted diffusion tensor imaging and constrained spherical deconvolution-based tractography to reconstruct the affected median nerve. Moreover, we extracted diffusion-based parameters reflecting axonal integrity loss of median nerve fibres. Our data showed that constrained spherical deconvolution-based tractography outperformed the diffusion tensor imaging-based method, allowing the detection of the entire median nerve, including its branches, thus offering a robust method to investigate the involvement of the median nerve in pathological conditions. All clinical and technical implications are extensively described.

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