We have located links that may give you full text access.
Novel synthesis of gold nanoparticles using Artemisia vulgaris L. leaf extract and their efficacy of larvicidal activity against dengue fever vector Aedes aegypti L.
Journal of Trace Elements in Medicine and Biology 2017 September
The Aedes aegypti L. mosquito transmits dengue and yellow fever, which cause millions of death every year. Dengue is a mosquito-borne viral disease that has rapidly spread worldwide particularly in countries with tropical and subtropical climates areas. The present study denotes a simple and eco-friendly biosynthesis of gold nanoparticles using Artemisia vulgaris L. leaf extract as reducing agent. The synthesized gold nanoparticles were characterized by UV-Visible Spectroscopy, X-Ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FT-IR), Dynamic Light Scattering (DLS), Zeta Potential (ZP), Transmission Electron Microscopy (TEM) and Energy Dispersive X-ray Spectroscopy (EDX). Solid state 13 C NMR was utilized to confirm the presence of larvicidal compound Beta caryophyllene in the synthesized AuNPs. Larvicidal activity of the synthesized AuNPs was measured against A. aegypti over 12 and 24h exposure periods and compared with essential oil in various concentrations (25ppm, 50ppm, 100ppm, 200ppm and 400ppm). After a 12h exposure period, the larvicidal activity of 3rd instar larva by AuNPs showed LC50 =156.55ppm and LC90 =2506.21ppm, while and essential oil displayed LC50 =128.99ppm and LC90 =1477.08ppm. Larvicidal activity of 4th instar larva by AuNPs showed LC50 =97.90ppm and LC90 =1677.36ppm, while essential oil displayed LC50 =136.15ppm and LC90 =2223.55ppm. After a 24h of exposure period, larvicidal activity of 3rd instar larva by AuNPs showed LC50 =62.47ppm and LC90 =430.16ppm and essential oil showed LC50 =111.15ppm and LC90 =1441.51ppm. The larvicidal activity of 4th instar larva and AuNPs displayed LC50 =43.01ppm and LC90 =376.70ppm and for essential oil LC50 =74.42ppm, LC90 =858.36ppm. Histopathology of A. aegypti with AuNPs for 3rd and 4th stage larvae after 24h exposure at the highest mortality concentration (400ppm) showed that the area of the midgut, epithelial cells and cortex were highly affected. The present findings demonstrate that the biosynthesis of AuNPs using A. vulgaris leaf extracts could be an eco-friendly, safer nanobiopesticide and treatment against A. aegypti which could be used to combat of dengue fever.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app