JOURNAL ARTICLE
REVIEW

Immunodeficiency Presenting as an Undiagnosed Disease

John M Routes, James W Verbsky
Pediatric Clinics of North America 2017, 64 (1): 27-37
27894450
Although primary immunodeficiencies typically present with recurrent, chronic, or severe infections, autoimmune manifestations frequently accompany these disorders and may be the initial clinical manifestations. The presence of 2 or more autoimmune disorders, unusual severe atopic disease, or a combination of these disorders should lead a clinician to consider primary immunodeficiency disorders.

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