Optical Coherence Tomography in Neuro-ophthalmology.

The afferent visual pathway is a functionally eloquent region of the central nervous system (CNS). Key clinical features of inflammatory, ischemic, and compressive CNS lesions can be appreciated through detailed ophthalmic examination. Optical coherence tomography (OCT) provides a noninvasive means of capturing manifestations of axonal and neuronal loss in the CNS. OCT represents a surrogate marker of structural integrity in the CNS, through which mechanisms of neurodegeneration and repair may be better understood. In this article, the role of OCT in facilitating the diagnosis and management of several CNS disorders is discussed.