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Dosage Adjustments Related to Young or Old Age and Organ Impairment.

James F Burris, Michael A Tortorici, Maja Mandic, Michael Neely, Michael D Reed
Journal of Clinical Pharmacology 2016 December
Differences in physiology related to young or old age and/or organ system impairment alter the absorption, distribution, metabolism, and excretion of many medications and consequently their effectiveness and toxicity. This module discusses common alterations in medication use and dosage that are required in the pediatric age group, in the elderly, and in patients with renal or hepatic disease.

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