JOURNAL ARTICLE
REVIEW

Treatment of ARDS With Prone Positioning

Eric L Scholten, Jeremy R Beitler, G Kim Prisk, Atul Malhotra
Chest 2017, 151 (1): 215-224
27400909
Prone positioning was first proposed in the 1970s as a method to improve gas exchange in ARDS. Subsequent observations of dramatic improvement in oxygenation with simple patient rotation motivated the next several decades of research. This work elucidated the physiological mechanisms underlying changes in gas exchange and respiratory mechanics with prone ventilation. However, translating physiological improvements into a clinical benefit has proved challenging; several contemporary trials showed no major clinical benefits with prone positioning. By optimizing patient selection and treatment protocols, the recent Proning Severe ARDS Patients (PROSEVA) trial demonstrated a significant mortality benefit with prone ventilation. This trial, and subsequent meta-analyses, support the role of prone positioning as an effective therapy to reduce mortality in severe ARDS, particularly when applied early with other lung-protective strategies. This review discusses the physiological principles, clinical evidence, and practical application of prone ventilation in ARDS.

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alex clavo

Las razones son fisiopatológicas. E. El hospital Regional de lambayeque se inicia este tipo de ventilación prima pero aún sin un protocolo definido

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