Anaesthetic Management of a Patient with Hereditary Angioedema

Mediha Türktan, Ersel Güleç, Zehra Hatipoğlu, Çağatay Küçükbingöz, Mustafa Yılmaz, Yasemin Güneş
Turkish Journal of Anaesthesiology and Reanimation 2014, 42 (4): 217-9
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Hereditary angioedema (HAE) is a rare autosomal dominant disorder caused by reduced activity of the C1 esterase inhibitor. Clinically, angioedema most often involves the upper extremities, face, neck and larynx. The most common cause of death is asphyxia related to laryngeal oedema. Attacks are triggered by many factors such as trauma, stress, infections and hormonal fluctuations. C1 esterase inhibitor concentrates, fresh frozen plasma (FFP), androgen steroids, quinine pathway inhibitors and antifibrinolytics can be used as treatment. In this case report, the anaesthetic management of a patient with hereditary angioedema undergoing laminectomy surgery is reported.

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