Cholangiolocellular Carcinoma of the Liver Exhibiting High F-18 FDG Uptake.

Cholangiolocellular carcinoma (CoCC) is a rare primary liver cancer. It is considered to originate from hepatic progenitor or stem cells. We report a rare case of a 74-year-old male with CoCC of the liver and duodenal gastrointestinal stromal tumor (GIST). Both tumors manifested tracer uptakes on F-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT); however, the uptake in hepatic tumor was extremely higher than that in the duodenal tumor. This finding was helpful to exclude the metastasis of GIST.