We have located links that may give you full text access.
JOURNAL ARTICLE
REVIEW
SYSTEMATIC REVIEW
Outcome reporting in randomized controlled trials and systematic reviews of gastroschisis treatment: a systematic review.
Journal of Pediatric Surgery 2016 August
BACKGROUND: Core outcome sets (COS) facilitate clinical research by providing an agreed set of outcomes to be measured when evaluating treatment efficacy. Gastroschisis is increasing in frequency and evidence-based treatments are lacking. We aimed to identify initial candidate outcomes for a gastroschisis COS from existing literature.
METHODS: Using a sensitive search strategy we identified randomized controlled trials (RCTs) and systematic reviews (SRs) of treatment interventions for gastroschisis. Outcomes were extracted and assigned to the core areas, 'Pathophysiological Manifestations', 'Life Impact', 'Resource Use', 'Adverse Events' and 'Mortality'.
RESULTS: A total of 50 outcomes were identified. RCTs reported 6-9 outcomes each; SRs reported 9-25. The most frequently reported outcomes were 'Length of hospital stay' (reported in 8 studies), 'Duration of ventilation' and 'Time to full enteral feeds' (7 studies). Outcomes identified could be assigned to all five core areas.
CONCLUSIONS: There is wide heterogeneity in outcomes reported in studies evaluating treatment interventions for gastroschisis. It is unclear which outcomes are of highest importance across stakeholder groups. Developing a COS to standardize outcome measurement and reporting for gastroschisis is warranted.
METHODS: Using a sensitive search strategy we identified randomized controlled trials (RCTs) and systematic reviews (SRs) of treatment interventions for gastroschisis. Outcomes were extracted and assigned to the core areas, 'Pathophysiological Manifestations', 'Life Impact', 'Resource Use', 'Adverse Events' and 'Mortality'.
RESULTS: A total of 50 outcomes were identified. RCTs reported 6-9 outcomes each; SRs reported 9-25. The most frequently reported outcomes were 'Length of hospital stay' (reported in 8 studies), 'Duration of ventilation' and 'Time to full enteral feeds' (7 studies). Outcomes identified could be assigned to all five core areas.
CONCLUSIONS: There is wide heterogeneity in outcomes reported in studies evaluating treatment interventions for gastroschisis. It is unclear which outcomes are of highest importance across stakeholder groups. Developing a COS to standardize outcome measurement and reporting for gastroschisis is warranted.
Full text links
Trending Papers
A Personalized Approach to the Management of Congestion in Acute Heart Failure.Heart International 2023
Potential Mechanisms of the Protective Effects of the Cardiometabolic Drugs Type-2 Sodium-Glucose Transporter Inhibitors and Glucagon-like Peptide-1 Receptor Agonists in Heart Failure.International Journal of Molecular Sciences 2024 Februrary 21
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app