Change in body mass index among girls with precocious puberty under treatment

Jessie N Zurita Cruz, Irene Díaz Rodríguez, Elisa Nishimura Meguro, Miguel Á Villasis Keever, Aleida De Jesús Rivera Hernández, Eulalia Garrido Magaña
Archivos Argentinos de Pediatría 2016, 114 (2): 143-5

INTRODUCTION: Changes in body mass index (BMI) among girls with idiopathic central precocious puberty (ICPP) under treatment have been controversial in other populations.

OBJECTIVE: To assess changes in BMI Z score and the rate of overweight and obesity in Mexican girls with ICPP during their first year of treatment.

METHODOLOGY: A retrospective study was conducted among girls with ICPP under treatment with leuprolide, with a somatometry performed every six months, over a 1-year period. An analysis of variance (ANOVA) was done to establish differences in BMI Z score and a multivariate analysis was used to assess the relationship among the different factors.

RESULTS: Among 121 girls, BMI Z score increased from 0.87 to 1.32, and the rate of overweight and obesity increased from 40.5% to 70.3%, a statistically significant difference.

CONCLUSIONS: Changes in BMI Z score and the rate of overweight and obesity among Mexican girls with ICPP increased significantly.

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