JOURNAL ARTICLE
REVIEW
Add like
Add dislike
Add to saved papers

The treatment of muscle-invasive bladder cancer in geriatric patients.

PURPOSE OF REVIEW: Bladder cancer is an age-related cancer and because of aging population, an increase of patients with muscle-invasive bladder cancer (MIBC) seems inevitable. Decisions regarding the treatment of geriatric patients with MIBC are complex and require a multidisciplinary approach.

RECENT FINDINGS: In addition to a specific urological oncology evaluation, a general geriatric evaluation is of great importance for all geriatric patients with MIBC. Standard of care in appropriate geriatric MIBC patients is radical cystectomy with urinary diversion and neoadjuvant platinum-based combination chemotherapy. There is evidence that adjuvant chemotherapy after surgery brings a benefit, but these data are less clear. An alternative to radical cystectomy, especially in elderly patients with concomitant disease, can be trimodal therapy, whereas the equality of this approach remains to be proven.

SUMMARY: Treatment decisions should not be based on the patient's chronological age alone, but rather on overall performance status, quality of life considerations, social performance, and patient preferences. On this account, patients should not be denied a potentially life-saving intervention just because they are elderly. The hope of personalized medicine and targeted therapy with less side-effects and complications may soon become a reality.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app