JOURNAL ARTICLE
REVIEW

Multiple Myeloma: Diagnosis and Treatment

S Vincent Rajkumar, Shaji Kumar
Mayo Clinic Proceedings 2016, 91 (1): 101-19
26763514
The diagnosis and treatment of multiple myeloma has changed dramatically in the past decade. The disease definition has been updated to include highly specific biomarkers in addition to established markers of end-organ damage. The staging system has been revised to combine both measures of tumor burden and disease biology. Advances in therapy have resulted in a marked improvement in overall survival. New drugs introduced in the past few years include carfilzomib, pomalidomide, panobinostat, ixazomib, elotuzumab, and daratumumab. In this review, we outline the current approach to the diagnosis, prognosis, and management of multiple myeloma.

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Nabeel Ahmed

Magnifique..

4

Jean Pinto Angarita

Excelente.

4

Sergio Zamora Varela

Excelente gracias

3

Bassam Francis

Where is VCD in low and intermediate risk groups?
Is there any difference between VCD and VRD regarding PFS and OS??

Thanks
Bassam Francis
Iraq

3

Edgar Delgado

Excelente

1

wei no

thank you very much

0

Lilia Rizo

Perfecto!!

0

Bogdan T

Very well done.

0

Aaron Plascencia Garcia

Excelente actualizaci├│n

0

Wojciech Legiec

Many thanks. Excelent rewiev.

0

Yamil Rodriguez

Excelente!! Muchas gracias!

0

David Gonzalez

Excelent

-1

Fernando Vasquez

Very good

-2

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