JOURNAL ARTICLE
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[Clinical diagnosis and treatment of primary retroperitoneal schwannoma: a report of 109 cases].

OBJECTIVE: To evaluate the surgical efficacies of primary retroperitoneal schwannoma (PRS) and analyze its risk factors for survival and recurrence.

METHODS: From January 1993 to December 2012, 109 patients diagnosed with primary retroperitoneal schwannoma were treated at our department. And their clinical data were retrospectively analyzed.

RESULTS: The overall 1,3,5-year survival rates of benign PRS were all 100%. Univariate analyses revealed that tumor size and modus operandi of tumor resection were associated with recurrence rate. For malignant PRS, the overall 1,3,5-year survival and recurrence rates were 89.6%, 62.1%, 41.4% and 41.4%, 65.5%, 72.4% respectively. Univariate analyses revealed that tumor size, modus operandi of tumor resection and tumor grade were associated with survival rate. Tumor grade was associated with recurrence rate and it was also an independent prognostic factor.

CONCLUSION: The major management of PRS is complete excision. Benign PRS has an excellent survival rate. And tumor size and modus operandi of tumor resection are associated with recurrence rate. The survival rate of malignant PRS is associated with tumor size, modus operandi of tumor resection and tumor grade. As an independent prognostic factor, tumor grade is associated with recurrence rate.

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