Isolated Tricuspid Regurgitation: Initial Manifestation of Cardiac Amyloidosis

Dong Woog Yoon, Byung-Jo Park, In Sook Kim, Dong Seop Jeong
Korean Journal of Thoracic and Cardiovascular Surgery 2015, 48 (6): 422-5
Amyloid deposits in the heart are not exceptional in systemic amyloidosis. The clinical manifestations of cardiac amyloidosis may include restrictive cardiomyopathy, characterized by progressive diastolic and eventually systolic bi-ventricular dysfunction; arrhythmia; and conduction defects. To the best of our knowledge, no previous cases of isolated tricuspid regurgitation as the initial manifestation of cardiac amyloidosis have been reported. We describe a rare case of cardiac amyloidosis that initially presented with severe tricuspid regurgitation in a 42-year-old woman who was successfully treated with tricuspid valve replacement. Unusual surgical findings prompted additional evaluation that established a diagnosis of plasma cell myeloma.

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