Hand rejuvenation.

Aging of the hands results from both natural processes and chronic ultraviolet light exposure. Together, these cause textural and pigmentary changes, excess skin laxity, rhytides, and soft tissue atrophy that presents as prominent bones and tendons with easily visible veins. Many options are available for the reversal of these changes. Photoaging can be improved with chemical peels and light-based treatments (such as Q-switched lasers), resurfacing lasers, intense pulsed light, and photodynamic therapy. Soft tissue atrophy can be corrected with autologous fat, nonanimal stabilized hyaluronic acid, calcium hydroxylapatite, and poly-L lactic acid injections. The literature shows that these treatments have favorable outcomes for most patients; but in order to reduce known complications, it is important to understand the proper use and limitations of each modality.