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JOURNAL ARTICLE
REVIEW
Splenectomy, pneumococcal vaccination and antibiotic prophylaxis.
British Journal of Hospital Medicine 1989 Februrary
Fulminant sepsis following splenectomy remains a major problem. Even with the administration of pneumococcal vaccine and prophylactic antibiotics fatalities still occur. A better understanding of the complex immunological function of the spleen, its preservation as much as possible during surgery, potent vaccine and perhaps more effective antibiotics will, hopefully, help reduce mortality in some of these cases in future.
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