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Controlled Clinical Trial
Journal Article
Ultrasonographic Features of the Major Salivary Glands after Radioactive Iodine Ablation in Patients with Papillary Thyroid Carcinoma.
Ultrasound in Medicine & Biology 2015 October
The aim of this study was to evaluate the ultrasonographic features of the major salivary glands (MSGs) after post-operative radioactive iodine ablation (RIA) in patients with papillary thyroid carcinoma (PTC). The study population comprised 202 consecutively registered PTC patients who had undergone total thyroidectomy, RIA and follow-up neck ultrasonography. The ultrasonographic features of the MSGs in each patient were retrospectively evaluated by a single radiologist, and the presence of post-RIA changes was determined by direct comparisons of pre- and post-RIA follow-up ultrasonographic scans. Of the 202 patients, 94 (46.5%) had post-RIA changes in the MSGs on follow-up ultrasonography. RIA dose was closely associated with the prevalence of post-RIA changes. Post-RIA changes were more common in the parotid glands (n = 93, 46.0%) than in the submandibular glands (n = 7, 3.5%). Common ultrasonographic findings representing post-RIA changes in MSGs included coarse echotexture, decreased echogenicity, lobulated margin and decreased gland size.
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