Neurobehavioral Sequelae of Psychostimulant Abuse.

Psychostimulants are a heterogeneous group of drugs known not only for its arousal and motor activity enhancing effects but also for its high risk of abuse. In susceptible individuals, chronic use can cause addiction leading to devastating physical, psychological, and social health consequences. This chapter will focus on the neurobehavioral consequences of psychostimulant abuse. Different models and theories of addiction and possible underlying mechanisms as well as changed in decision making on neuropsychological tasks have been discussed. Prevention and early behavioral intervention are of paramount importance given the lack of approved drug therapies for these patients.