JOURNAL ARTICLE
REVIEW

Sugammadex: A revolutionary drug in neuromuscular pharmacology

Kusha Nag, Dewan Roshan Singh, Akshaya N Shetti, Hemanth Kumar, T Sivashanmugam, S Parthasarathy
Anesthesia, Essays and Researches 2013, 7 (3): 302-6
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Sugammadex (ORG 25969) is a unique neuromuscular reversal drug; a novel cyclodextrin, the first in a new class of selective relaxant binding agents, which reverse neuromuscular blockade (NMB) with the aminosteroid non-depolarizing muscle relaxants rocuronium and vecuronium. Sugammadex can reverse moderate or deep NMB. The clinical use of sugammadex promises to eliminate many of the shortcomings in current anesthetic practice with regard to antagonism of rocuronium and other aminosteroid muscle relaxants.

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