JOURNAL ARTICLE

Starling curves and central venous pressure

David A Berlin, Jan Bakker
Critical Care: the Official Journal of the Critical Care Forum 2015, 19 (1): 776
25777871
Recent studies challenge the utility of central venous pressure monitoring as a surrogate for cardiac preload. Starting with Starling's original studies on the regulation of cardiac output, this review traces the history of the experiments that elucidated the role of central venous pressure in circulatory physiology. Central venous pressure is an important physiologic parameter, but it is not an independent variable that determines cardiac output.

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