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Journal Article
Review
Glioma in 2014: unravelling tumour heterogeneity-implications for therapy.
Nature Reviews. Clinical Oncology 2015 Februrary
Heterogeneity within and across tumours is increasingly recognized as a critical factor that limits therapeutic progress for many cancers. Key studies reported in 2014 describe previously unappreciated patterns of geographical and temporal heterogeneity for glioblastoma (the most-common primary CNS tumour in adults), with important implications for ongoing therapeutic studies evaluating molecular targeted therapies.
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