Development of human neutralizing monoclonal antibodies for prevention and therapy of MERS-CoV infections

Tianlei Ying, Haoyang Li, Lu Lu, Dimiter S Dimitrov, Shibo Jiang
Microbes and Infection 2015, 17 (2): 142-8
The recent Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak poses a serious threat to public health. Here, we summarize recent advances in identifying human neutralizing monoclonal antibodies (mAbs) against MERS-CoV, describe their mechanisms of action, and analyze their potential for treatment of MERS-CoV infections.

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