We have located links that may give you full text access.
JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Are cases of Methicillin-resistant Staphylococcus aureus clonal complex (CC) 398 among humans still livestock-associated?
International Journal of Medical Microbiology : IJMM 2015 January
UNLABELLED: Methicillin-resistant Staphylococcus aureus (MRSA) of clonal complex (CC) 398 are widespread among pigs, cattle and poultry as well as among humans who have contact to these livestock animals. However, there is limited data on livestock-independent dissemination of MRSA CC398 in the general population.
METHODS: In this case-control study MRSA isolates derived (between July 2013 and June 2014) from patients of four hospitals located in a livestock-dense region were S. aureus protein A (spa) typed and risk factors for MRSA acquisition were assessed from patients colonized or infected with MRSA CC398 vs. other MRSA molecular types (MRSA non-CC398).
RESULTS: Of 384 patients, 21% were colonized with MRSA CC398. Contact with livestock (Odds Ratio (OR) 46.03) and residence directly on a pig farm (OR 12.82) were associated with MRSA CC398. Of 55 patients with MRSA CC398, 21 (38%) did not report direct livestock contact. Among the latter we identified several risk factors that could have facilitated indirect transmission, such as living on farms (without being farmer), private contact with known MRSA carriers or previous hospitalization.
DISCUSSION: This study suggests that MRSA CC398 is still mostly disseminated via direct contact to livestock. However, a substantial proportion of patients seem to acquire MRSA CC398 via other pathways.
METHODS: In this case-control study MRSA isolates derived (between July 2013 and June 2014) from patients of four hospitals located in a livestock-dense region were S. aureus protein A (spa) typed and risk factors for MRSA acquisition were assessed from patients colonized or infected with MRSA CC398 vs. other MRSA molecular types (MRSA non-CC398).
RESULTS: Of 384 patients, 21% were colonized with MRSA CC398. Contact with livestock (Odds Ratio (OR) 46.03) and residence directly on a pig farm (OR 12.82) were associated with MRSA CC398. Of 55 patients with MRSA CC398, 21 (38%) did not report direct livestock contact. Among the latter we identified several risk factors that could have facilitated indirect transmission, such as living on farms (without being farmer), private contact with known MRSA carriers or previous hospitalization.
DISCUSSION: This study suggests that MRSA CC398 is still mostly disseminated via direct contact to livestock. However, a substantial proportion of patients seem to acquire MRSA CC398 via other pathways.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app