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Neuroimmunology: towards more-accurate diagnosis in neuromyelitis optica.

Kazuo Fujihara, Jacqueline Palace
Nature Reviews. Neurology 2014 December
Neuromyelitis optica spectrum disorders (NMOSD) can mimic multiple sclerosis (MS). Avoiding misdiagnosis is crucial, because some disease-modifying drugs for MS can aggravate NMOSD, causing blindness and paraplegia. A recent study reports that misdiagnosis of NMOSD as MS occasionally occurs, and that a two-step antibody assay could improve differential diagnosis.

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